Что (кто) такое mutation - определение

CHANGE OF THE NUCLEOTIDE SEQUENCE OF THE GENOME OF AN ORGANISM

Mutations; Genetic mutation; Mutates; Mutate; Mutation and disease; Gene mutation; Loss-of-function mutation; Gain-of-function mutation; Neomorphic mutation; Antimorphic mutation; Amorphic mutation; Loss-of-function; Mutant allele; Genetic mutations; Conditional lethal mutation; Conditional mutation; Mutation event; Loss of function; Mutated; Spontaneous mutation; Mutant proteins; Nuclear mutation; Reversion (genetics); Genetic damage; DNA mutations; Chromosomal gain; Beneficial mutation; Acquired genetic mutation; Reverse mutation; Genetic changes; Mutating; Viral mutation; Backmutation; Back-mutation; Gene mutation analysis; Extragenic; Radiation genetics; Mutant Proteins; DNA error; In-frame mutation; In-frame deletion; DNA mutation; Mutational; Distribution of fitness effects; Types of mutation; Sporadic mutation; Harmful mutation; Deleterious mutation; Sport (genetics); Mutation (biology); Inactivating mutation; De novo mutations; Activating mutations; Mutant spectrum; Deformation (biology); Loss-of-function mutant; Gain of function mutation; Substitution (genetics); Loss of function mutation

mutation

1) to induce a mutation

2) a gene mutation

mutation

¦ noun

1. the action or process of changing in form or nature.

a change.

2. a change in the structure of a gene resulting in a variant form which may be transmitted to subsequent generations.

a distinct form resulting from genetic mutation.

3. Linguistics (in Celtic languages) change of an initial consonant in a word caused by the preceding word.

(in Germanic languages) the umlaut process.

Derivatives

mutational adjective

mutationally adverb

Origin

ME: from L. mutatio(n-), from mutare 'to change'.

mutation

see mutate

Википедия

Mutation

In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements.

Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source of all genetic variation, providing the raw material on which evolutionary forces such as natural selection can act.

Mutation can result in many different types of change in sequences. Mutations in genes can have no effect, alter the product of a gene, or prevent the gene from functioning properly or completely. Mutations can also occur in non-genic regions. A 2007 study on genetic variations between different species of Drosophila suggested that, if a mutation changes a protein produced by a gene, the result is likely to be harmful, with an estimated 70% of amino acid polymorphisms that have damaging effects, and the remainder being either neutral or marginally beneficial. Due to the damaging effects that mutations can have on genes, organisms have mechanisms such as DNA repair to prevent or correct mutations by reverting the mutated sequence back to its original state.

https://en.wikipedia.org/wiki/Mutation

Примеры произношения для mutation